A Secret Weapon For ceesdekker
A Secret Weapon For ceesdekker
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‘Sure, that is definitely about correct. I seek for a physical comprehension of Organic methods in a very base-up way. I believe you could possibly distinguish three lines of investigation in my team in the meanwhile. The first considerations chromosome framework: how do you obtain a metre-prolonged DNA polymer folded and organised in this kind of microscopic cell? We now have made visualisation techniques that enable us to review how, for example, SMC proteins loop DNA (video on Youtube) as a way to Make up chromosomes.
Our group scientific studies bacterial cell division and is particularly aiming to represent a ‘bottom up biology’ in synthetic cells which can autonomously divide. Our most important fascination lies in cell division, chromatin structure, and spatial control.
Being a individual, I have the biblical assignment to investigate and use anything in creation for the benefit of my neighbour. I usually do not working experience any conflict among religion and science. Quite the opposite, my religion stimulates me to do science, to become open-minded on the earth.’
Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on solitary molecules and metallic clusters
2015, discovery that condensin is actually a extremely adaptable protein framework; and initial detection of DNA knots using nanopores
The coiled-coil of your human Rad50 DNA mend protein consists of unique segments of enhanced flexibility
MATLAB codes for knowledge processing can be found at . Julia codes useful for numerical simulation can be obtained at .
Atomic power microscopy demonstrates that vaccinia topoisomerase IB generates filaments on DNA inside of a cooperative style
Comprehension elementary procedures regulating the spatial and dynamic organisation on the DNA in Stay cells.
But carbon nanotubes have remained a study topic of considerable interest to many. In truth, the outlook on applying carbon nanotubes to make realistic products, in regions for example radio-frequency electronics, digital electronics and flexible electronics, continues to be shiny.
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
‘That considerations the artificial mobile, as Portion of the Dutch BaSyC initiative. Craig Venter appeared leading-down in All those days and recognized about 5 hundred genes that are minimally essential for just a working mobile. We wish to look bottom-up: how can we shift from a number of molecules to an entire Organic method?
2005, discovery on the system of DNA uncoiling by topoisomerase enzymes; discovery of extended-vary conformational adjustments in Mre11/DNA maintenance complexes; and initial pressure measurements on a DNA molecule within a nanopore
Last but not least, I'll briefly sketch several of ceesdekker.net our Strategies to take a look at the building of synthetic cells, specifically our initial measures to establish synthetic cell division.